There were cruises to Cuba from Charleston for a short period, but government regulations shut them down.
Cuba "people to people" cruise excursions included Havana community art projects, food tasting & modern dance, cigars & rum, Havana sites tour, Las Terrazas valley tour, colonial past tour, Cuban music experience, Tropicana Cabaret, Buena Vista Social Club, Hemingway tour, or preserved old cars experience.